4-coumarate:Coenzyme A ligase (4CL) plays an important role in lignin biosynthetic pathway that catalyzed the activation of coumaric acid. caffeic acid or ferulic acid to be a syringil monomer. Lignin biosynthesis control through 4CL down regulating would support lower lignin wood production. The objective of this study was to clone conserved region cDNA of gene encoding 4CL. https://parisnaturalfoodes.shop/product-category/shark-liver-oil/