Abstract The extracellular activity of Plasminogen activator inhibitor-1 (PAI-1) is well described. acting as an inhibitor of tissue plasminogen activator and urokinase-type plasminogen activator. impacting fibrinolysis. Recent studies have revealed a pro-tumorigenic role of PAI-1 in human cancers. https://www.marcelovicente.com/product-category/eyelash-curler/